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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN2 All Species: 6.06
Human Site: T304 Identified Species: 10.26
UniProt: Q16513 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16513 NP_006247.1 984 112035 T304 S L V A A S P T L S P R Q S M
Chimpanzee Pan troglodytes XP_001145367 984 112028 T304 S L V A A S P T L S P R Q S M
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 P358 Q L L E Q L P P A H P L R S R
Dog Lupus familis XP_547295 1021 115999 L342 S L V A S P T L S P R Q S M I
Cat Felis silvestris
Mouse Mus musculus Q8BWW9 983 111611 L304 S L V A S P T L S P R Q S M L
Rat Rattus norvegicus O08874 985 112050 L306 S L V A S P T L S P R Q S M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 A345 R L A A E L P A A H P T R S L
Chicken Gallus gallus XP_422357 1013 114806 L331 S L V S S P T L S P R Q S V I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700704 970 110327 L296 S L M S S P A L S P R Q S F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 F80 H Q G K A I G F S V F H S C V
Sea Urchin Strong. purpuratus XP_787090 799 90414 I172 C Q D L Q E M I P Y R A R N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 A348 S A I Q S T S A K N V Q G E N
Red Bread Mold Neurospora crassa P87253 1142 127954 Y316 N E I E F T V Y D K P A E H P
Conservation
Percent
Protein Identity: 100 99.6 46.1 92.8 N.A. 94.6 92.6 N.A. 53.9 87 N.A. 76.4 N.A. 28.3 N.A. 27.6 48.4
Protein Similarity: 100 99.9 63.2 94.7 N.A. 97.2 95.3 N.A. 68.2 91.9 N.A. 85 N.A. 42.3 N.A. 43.7 61.3
P-Site Identity: 100 100 26.6 26.6 N.A. 26.6 26.6 N.A. 33.3 20 N.A. 13.3 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 100 40 46.6 N.A. 46.6 46.6 N.A. 46.6 46.6 N.A. 46.6 N.A. 0 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 27.2
Protein Similarity: N.A. N.A. N.A. N.A. 45.6 45.9
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 43 22 0 8 15 15 0 0 15 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 8 0 15 8 8 0 0 0 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 8 0 0 8 0 0 8 0 0 8 0 % F
% Gly: 0 0 8 0 0 0 8 0 0 0 0 0 8 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 15 0 8 0 8 0 % H
% Ile: 0 0 15 0 0 8 0 8 0 0 0 0 0 0 22 % I
% Lys: 0 0 0 8 0 0 0 0 8 8 0 0 0 0 0 % K
% Leu: 0 65 8 8 0 15 0 36 15 0 0 8 0 0 22 % L
% Met: 0 0 8 0 0 0 8 0 0 0 0 0 0 22 15 % M
% Asn: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % N
% Pro: 0 0 0 0 0 36 29 8 8 36 36 0 0 0 8 % P
% Gln: 8 15 0 8 15 0 0 0 0 0 0 43 15 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 43 15 22 0 8 % R
% Ser: 58 0 0 15 43 15 8 0 43 15 0 0 43 29 8 % S
% Thr: 0 0 0 0 0 15 29 15 0 0 0 8 0 0 0 % T
% Val: 0 0 43 0 0 0 8 0 0 8 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _